Publishchemidea, 2014 No: 6
Submitted: Monday, January 27th, 2014
Title of the idea: |
Dehydration (esterification) and re-hydration (of alkyne) in one pot |
Author of the idea: |
Ramesha |
Email of the author |
ramesha63@hotmail.com |
Key words for search: |
Dehydration, rehydration, acid, acetone, alkyne |
Explain briefly the idea |
This is one pot conversion of alcohol to ester and acetylene to ketone. Water liberated in the esterification is consumed in alkyne hydrolysis. Different alkynes and alcohols can be tried. This will provide an easy access to mono substituted acetone
|
Why do you think this idea will work? |
This will provide an easy access to mono substituted acetone. Two reactions are done in one pot. |
Do you have any experimental proof? |
preliminary experiment shows the right product formation at 60% yield. |
Literature reference |
Pankaj Dawar, M Bagavan Raju, Ramesha A. R, Tettrahedron Lett, 2011, 52, 4262-4265 |
Where it is useful? |
Academic |
Do you plan to work on this idea in near future? |
Yes |
Interested in collaboration? |
No |
Nature of idea: |
Experimental |
Youtube link: |
|
Download article as PDF