Publishchemidea, 2014 No: 5

Submitted: Thursday, January 16th, 2014

Title of the idea: Dibenzosuberone -Hydrogen acceptor and hydrogen giver
Author of the idea: Ramesha
Email of the author
Key words for search: dehydrogenation, transfer hydrogenation, Dibenzosuberone, Dibenzosuberenone, palladium, Pd-C
Explain briefly the idea

Dibenosuberone is non aromatic. This can easily lose 2 hydrogen and become This reaction comes under transfer hydrogenation/dehydrogenation. Dibenzosuberenone (non-aromatic). In the absence of hydrogen acceptor (it is known that in the presence of hydrogen acceptor like dibutyl maleate, exclusive dibenzosuberenone is formed as per the attached reference). Dibenzosuberenone itself can act as hydrogen acceptor.

Why do you think this idea will work? Dibenzosubarene is a pharmaceutical impurity of Cyproheptadine. This could be the easiest method to synthesise this compound.
Do you have any experimental proof? Preliminary experiment shows this reaction works.
Literature reference S. Lambrecht, H. Surburg, US Patent, 6,617,473, 2003
Where it is useful? Industry
Do you plan to work on this idea in near future? Yes
Interested in collaboration? No
Nature of idea: Theoretical/experimental
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