Publishchemidea, 2014 No: 13

Submitted: Tuesday, July 15th, 2014

Title of the idea: Synthesis of L-Diphenylprolinol
Author of the idea: Ramesha
Email of the author
Key words for search: Prolinol, CBS, Grignard
Explain briefly the idea

Simple methof of synthesis of L-Prolinol (CBS catalyst) from an intermediate generated from L-Proline and triethylorthoacetate. Compared to other methods, this will be a simple procedure if it works!

Why do you think this idea will work? Simple method compared to known literature procedure
Do you have any experimental proof? This reaction does not work with triethylorthoacetate.
Literature reference J. V. Bhaskar K and M. Periasamy, Tetrahedron, 1993, 49(23), 5127-32
Where it is useful? Academic
Do you plan to work on this idea in near future? Yes
Interested in collaboration? Yes
Nature of idea: Theoretical/experimental
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